Dry, sweat-free underarm after Botox treatment for excessive sweating at Florida Aesthetics and Wellness in Brandon, FL

Hyperhidrosis · Neurotoxin · Brandon, FL

Botox for
Excessive Sweating

FDA-approved Botox treatment that stops excessive underarm sweating (hands and feet off-label) for 6–12 months. No surgery, no downtime, results in days.

Book a Free Consultation Call (813) 345-4044

6–12mo

duration of effect

2–4 days

onset of dryness

82%

reduction in sweating (clinical)

Underarm Sweating

FDA-approved · 6–12 month relief

Palmar hyperhidrosis, excessive hand sweating

Hand Sweating (Palmar)

Off-label · 4–6 month relief

About This Treatment

How does Botox stop excessive sweating?

Botox blocks the nerve signals that tell your eccrine sweat glands to activate. For patients with hyperhidrosis, this provides dramatic, often life-changing, relief from excessive underarm, hand, or foot sweating that doesn't respond to antiperspirants.

Hyperhidrosis is a medical condition affecting approximately 5% of the population, characterized by sweating that significantly exceeds what your body needs for thermoregulation. When antiperspirants and medications fail, Botox is the most clinically proven non-surgical solution available.

The FDA approved Botox specifically for primary axillary hyperhidrosis (excessive underarm sweating) in 2004. Clinical trials demonstrated an average 82% reduction in sweating. Off-label use for palmar (hand) and plantar (foot) hyperhidrosis is also well-documented with excellent safety and efficacy data.

What does Hyperhidrosis Botox treat?

Underarm hyperhidrosis (FDA-approved)
Palmar hyperhidrosis (excessive hand sweating)
Plantar hyperhidrosis (excessive foot sweating)
Craniofacial hyperhidrosis (forehead, scalp)
Compensatory hyperhidrosis (off-label)

Why patients choose Florida Aesthetics and Wellness

FDA-approved for underarms
82% average sweat reduction
Results within days
6–12 month duration
Licensed medical providers
Allē points eligible

Loyalty Program

Earn Allē Points on Hyperhidrosis Botox

Botox treatments for hyperhidrosis, including underarm, hand, and foot, earn Allē loyalty points. Redeem toward future Botox or Juvéderm treatments.

Learn About Allē →

What to Expect

Treatment experience by area

Underarm and palmar hyperhidrosis are both highly treatable, here's what each appointment looks like.

Underarm Hyperhidrosis

Excessive sweating that soaks through clothing, leaves visible stains, and isn't controlled by prescription antiperspirants. The FDA-approved Botox indication, with an 82% average reduction in sweating.

Starch-iodine mapping (optional)

Precisely maps the active sweat zone for optimal grid placement. Often skipped at follow-up sessions once the pattern is established.

Topical numbing (10–15 min)

Underarms are well-tolerated with numbing cream alone. No nerve block required for most patients.

Grid injections (~15 min)

~50 units per underarm in a grid pattern, approximately 15–20 injection points per side at 1–2 cm spacing.

Results in 2–4 days

Full dryness at 1–2 weeks. Duration 6–12 months. Complimentary touchup at 2 weeks for any remaining active zones.

Palmar hyperhidrosis Botox treatment for hands

Palmar Hyperhidrosis (Hands)

Sweaty palms that interfere with handshakes, writing, typing, and daily confidence. Often the most socially disruptive form of hyperhidrosis, and one of the most rewarding to treat.

Wrist nerve block for comfort

Palmar treatment is more sensitive due to high nerve density in the hands. A wrist nerve block is offered to ensure a comfortable experience throughout.

Grid injections (~20 min)

50–75 units per hand injected across the entire palm. Both hands are treated in the same appointment.

Mild temporary grip changes

Some patients notice brief, mild weakness in grip or fine motor tasks for a few days as nearby muscles adjust. This resolves on its own within a week.

Dry hands in 2–5 days

Duration is typically 4–6 months for hands. Follow-up included at 2 weeks to address any remaining active areas.

Hyperhidrosis Treatments Compared

How does Hyperhidrosis Botox compare to alternatives?

Understanding all available options before committing to a treatment approach.

Treatment	Efficacy	Duration	Downtime	FDA Approved
Botox injections	82% average reduction	6–12 months	None	✓ Yes (underarms)
Prescription antiperspirants (20–30% Al)	Moderate	Requires daily use	None	✓ Yes
miraDry (microwave)	High (permanent)	Permanent (results don't fade)	3–7 days	✓ Yes
Oral anticholinergics	Moderate	Daily medication	Systemic side effects	Yes (for other uses)
ETS surgery	Very high	Permanent	Significant	Yes (for hyperhidrosis)
Iontophoresis (electrical)	Moderate (hands/feet)	Requires sessions 2–3×/wk	None	Yes

Common Questions

Botox for Sweating, Frequently Asked Questions

Most patients notice a significant reduction in sweating within 2–4 days of treatment. Full effect is typically reached at 1–2 weeks. The onset is faster than cosmetic Botox for wrinkles because the mechanism (blocking the cholinergic signal to sweat glands) has a quicker clinical expression.

Yes. Blocking eccrine glands in the underarms does not impair your body's ability to regulate temperature. The human body has 2–4 million sweat glands across the entire body surface. The underarm region contains only a fraction of these. Eliminating underarm sweating shifts a negligible amount of heat dissipation to other areas, clinically insignificant for health.

Clinical studies show duration of 6–12 months for axillary hyperhidrosis. Individual factors affect duration: people with very active sweat glands may see shorter duration; cooler climates or less physical activity extend duration. Most patients treat 1–2 times per year, often scheduling before summer.

The underarms are reasonably comfortable with topical numbing cream. Hand and foot treatments are more sensitive, these have higher nerve density. For palmar and plantar treatments, we offer nerve blocks to ensure comfort. Many patients describe hand treatment as the most challenging but report it's absolutely worth the comfort once the results kick in.

Yes, deodorant and antiperspirant can be used as normal after treatment (though most hyperhidrosis patients find they need them far less or not at all). There are no restrictions on underarm products post-treatment. The standard post-Botox restrictions apply: avoid vigorous exercise for 24 hours and don't massage the treated area immediately after.

Palmar hyperhidrosis is excessive sweating of the hands, palms that are persistently damp or dripping, making handshakes uncomfortable and daily tasks frustrating. It's one of the most socially disruptive forms of hyperhidrosis. Botox is injected in a grid pattern across the palm, blocking the nerve signals to eccrine sweat glands. Results appear within 2–5 days and typically last 4–6 months. A wrist nerve block is offered before treatment to ensure comfort, since the palms have higher nerve density than the underarms.

Yes. Underarm (axillary) Botox typically lasts 6–12 months, the longest duration of any hyperhidrosis treatment area. Palmar (hand) Botox tends to last 4–6 months, as hands are used constantly and the muscle activity around the injection sites may accelerate metabolism of the toxin. Both are still significantly longer-lasting than other treatment options.

Botox for primary axillary hyperhidrosis is FDA-approved and may be covered by some insurance plans when performed in a medical setting with proper diagnosis. At Florida Aesthetics and Wellness, treatment is self-pay. If you have insurance that covers hyperhidrosis treatment, we recommend checking with your insurer about in-network providers. We offer Cherry financing for patients who prefer to spread out costs.

Curious about cost? Pricing depends on your specific treatment plan, which we map out at your consultation. The treatment you’re interested in might be on sale this month, so see our pricing page for current rates and check this month’s specials.

See Botox & filler costs This Month’s Specials

Ready to Book?

Start with a complimentary consultation, no obligation

We'll evaluate your goals, explain exactly what Hyperhidrosis Botox can and can't achieve for you, and provide a personalized treatment plan with transparent pricing.

Book a Free Consultation Call (813) 345-4044

Stay in the loop

Get the latest treatments, provider tips, and news from Florida Aesthetics & Wellness delivered to your inbox.

Botox forExcessive Sweating